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Apoptotic Signaling in Response to DNA Damage

KUGI Hs.76366 KUGI Hs.76366 h_aktPathway h_p53Pathway KUGI Hs.159428 KUGI Hs.151777 KUGI Hs.300825 KUGI Hs.305890 KUGI Hs.79241 KUGI Hs.159428 KUGI Hs.141125 KUGI Hs.3280 KUGI Hs.9216 KUGI Hs.300825 KUGI Hs.300825 KUGI Hs.408312 KUGI Hs.526394 KUGI Hs.526394 KUGI Hs.375001 h_caspasepathway KUGI Hs.177766 KUGI Hs.21486 KUGI Hs.446336 KUGI Hs.349611 KUGI Hs.434281 KUGI Hs.159428 KUGI Hs.289271 KUGI Hs.305890 KUGI Hs.79241 KUGI Hs.368861 KUGI Hs.373575 KUGI Hs.329502 KUGI Hs.408312

Original NCI CGAP BioCarta Pathway


There are 22 genes in this pathway and 22 of them were found in Korean UniGene Collection

GeneKUGIGenBankUniGeneCGAPName
ADPRTKU002389
KU011804
hMU004762
NM_001618Hs.177766177766ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
AKT1KU002096
KU003970
KU017317
hMU005765
NM_005163Hs.368861368861v-akt murine thymoma viral oncogene homolog 1
APAF1KU023875NM_181869
NM_181868
NM_181861
NM_001160
NM_013229
Hs.373575373575apoptotic protease activating factor
ATMKU028786
KU031599
hMU009468
NM_000051
NM_138293
NM_138292
Hs.526394526394ataxia telangiectasia mutated (includes complementation groups A, C and D)
BADKU011879
KU034939
hIU007340
hMU006974
NM_004322
NM_032989
Hs.7636676366BCL2-antagonist of cell death
BAXKU010194
KU011138
hMU011946
NM_004324
NM_138765
NM_138764
NM_138763
NM_138762
NM_138761
Hs.159428159428BCL2-associated X protein
BCL2KU019136
hIU006963
hMU003583
NM_000633
NM_000657
Hs.7924179241B-cell CLL/lymphoma 2
BCL2KU019136
hIU006963
hMU003583
BC027258Hs.501181501181B-cell CLL/lymphoma 2
BCL2L1KU000985
KU006461
KU015237
KU018890
hMU010045
NM_001191
NM_138578
Hs.305890305890BCL2-like 1
BIDKU003367
KU025786
KU033624
KU034146
hMU002674
hMU003203
hMU005162
hMU011071
NM_197967
NM_197966
NM_001196
Hs.300825300825BH3 interacting domain death agonist
CASP3KU013419
KU023038
hIU000900
hIU002050
hIU002136
hIU003736
hIU003766
hMU001937
NM_004346
NM_032991
Hs.141125141125caspase 3, apoptosis-related cysteine protease
CASP6KU011665
KU023158
hIU007293
hMU005524
hMU008684
hMU009660
NM_001226
NM_032992
Hs.32803280caspase 6, apoptosis-related cysteine protease
CASP7KU014899
KU016438
KU023002
hMU001094
NM_001227
NM_033340
NM_033339
NM_033338
Hs.92169216caspase 7, apoptosis-related cysteine protease
CASP9hMU006278
hMU008136
NM_001229
NM_032996
Hs.329502329502caspase 9, apoptosis-related cysteine protease
CYC1KU000924
KU012808
KU015611
KU019568
KU020426
KU026102
KU026261
KU026459
KU026516
KU028453
hMU001304
hMU005616
hMU012294
NM_001916Hs.289271289271cytochrome c-1
EIF2S1KU000546
KU006941
KU027294
KU027368
hIU003524
hIU007462
hIU007518
hMU006136
NM_004094Hs.151777151777eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
PRKCAKU007246
KU007446
KU029981
NM_002737Hs.349611349611protein kinase C, alpha
PTK2KU006020
KU008558
KU009656
KU011415
KU030818
hMU002669
hMU004475
NM_005607
NM_153831
Hs.434281434281PTK2 protein tyrosine kinase 2
PXNKU001144
KU002813
KU008132
KU016281
KU021054
hMU001154
NM_002859Hs.446336446336paxillin
STAT1KU006604
KU008152
KU009024
KU009821
KU031937
hMU007445
NM_007315
NM_139266
Hs.2148621486signal transducer and activator of transcription 1, 91kDa
TLN1KU027236
KU028856
KU030130
NM_006289Hs.375001375001talin 1
TP53KU001989
KU002550
hMU007060
NM_000546Hs.408312408312tumor protein p53 (Li-Fraumeni syndrome)