KU_BioCarta Pathways

Pathways and Clones

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KU_BioCarta Pathways
for human cellular processes

Pathway information provided by KUGI and BioCarta
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For information on sources of Pathway diagrams, see Biocarta Pathways HowTo

A B C D E F G H I K L M N O P R S T U V W Y beta

Numbers in [ ] are total and KUGI Human genes in the pathway

Acetylation and Deacetylation of RelA in The Nucleus [13/12]
Actions of Nitric Oxide in the Heart [17/12]
Activation of cAMP-dependent protein kinase, PKA [6/5]
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor [16/9]
Activation of PKC through G protein coupled receptor [5/4]
Activation of Src by Protein-tyrosine phosphatase alpha [8/7]
Acute Myocardial Infarction [13/9]
Adhesion and Diapedesis of Granulocytes [15/11]
Adhesion and Diapedesis of Lymphocytes [13/9]
Adhesion Molecules on Lymphocyte [9/7]
ADP-Ribosylation Factor [16/14]
Agrin in Postsynaptic Differentiation [29/22]
Ahr Signal Transduction Pathway [4/4]
AKAP95 role in mitosis and chromosome dynamics [10/7]
AKT Signaling Pathway [19/12]
ALK in cardiac myocytes [34/25]
Alpha-synuclein and Parkin-mediated proteolysis in Parkinson's disease [2/1]
Alternative Complement Pathway [9/2]
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling [28/25]
Angiotensin-converting enzyme 2 regulates heart function [9/2]
Anthrax Toxin Mechanism of Action [3/2]
Antigen Dependent B Cell Activation [11/4]
Antigen Processing and Presentation [7/5]
Apoptotic DNA fragmentation and tissue homeostasis [9/8]
Apoptotic Signaling in Response to DNA Damage [22/21]
Aspirin Blocks Signaling Pathway Involved in Platelet Activation [20/15]
ATM Signaling Pathway [19/18]
Attenuation of GPCR Signaling [7/5]

B Cell Receptor Complex [0/0]
B Cell Survival Pathway [15/14]
B Lymphocyte Cell Surface Molecules [10/5]
Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression [4/4]
Basic Mechanisms of SUMOylation [5/5]
BCR Signaling Pathway [26/23]
Bioactive Peptide Induced Signaling Pathway [30/27]
Blockade of Neurotransmitter Relase by Botulinum Toxin [4/4]
Bone Remodelling [14/12]
BRCA1-dependent Ub-ligase activity [9/9]
BTG family proteins and cell cycle regulation [10/9]
Bystander B Cell Activation [7/3]

Ca++/ Calmodulin-dependent Protein Kinase Activation [5/5]
Cadmium induces DNA synthesis and proliferation in macrophages [14/14]
Calcium Signaling by HBx of Hepatitis B virus [8/8]
Cardiac Protection Against ROS [4/3]
CARM1 and Regulation of the Estrogen Receptor [26/23]
Caspase Cascade in Apoptosis [23/21]
Catabolic Pathways for Arginine , Histidine, Glutamate, Glutamine, and Proline [6/6]
Catabolic Pathways for Methionine, Isoleucine, Threonine and Valine [4/4]
CBL mediated ligand-induced downregulation of EGF receptors [11/9]
CCR3 signaling in Eosinophils [22/15]
CD40L Signaling Pathway [14/13]
cdc25 and chk1 Regulatory Pathway in response to DNA damage [7/6]
CDK Regulation of DNA Replication [8/7]
Cell Cycle: G1/S Check Point [28/25]
Cell Cycle: G2/M Checkpoint [22/21]
Cell to Cell Adhesion Signaling [10/9]
Cells and Molecules involved in local acute inflammatory response [17/12]
Ceramide Signaling Pathway [22/21]
Chaperones modulate interferon Signaling Pathway [16/13]
ChREBP regulation by carbohydrates and cAMP [9/5]
Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes [18/18]
Circadian Rhythms [5/5]
Classical Complement Pathway [11/4]
Complement Pathway [16/6]
Control of Gene Expression by Vitamin D Receptor [27/26]
Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK) [17/15]
Corticosteroids and cardioprotection [14/10]
CTCF: First Multivalent Nuclear Factor [18/14]
CTL mediated immune response against target cells [13/6]
CXCR4 Signaling Pathway [22/19]
Cyclin E Destruction Pathway [9/9]
Cycling of Ran in nucleocytoplasmic transport [5/5]
Cyclins and Cell Cycle Regulation [24/22]
Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway [8/7]
Cytokine Network [21/9]
Cytokines and Inflammatory Response [27/13]

D4-GDI Signaling Pathway [13/11]
Degradation of the RAR and RXR by the proteasome [3/3]
Dendritic cells in regulating TH1 and TH2 Development [21/5]
Deregulation of CDK5 in Alzheimers Disease [9/8]
Dicer Pathway [5/4]
Double Stranded RNA Induced Gene Expression [9/9]
Downregulated of MTA-3 in ER-negative Breast Tumors [14/12]

E2F1 Destruction Pathway [10/9]
Effects of calcineurin in Keratinocyte Differentiation [10/9]
EGF Signaling Pathway [26/25]
Eicosanoid Metabolism [21/8]
Electron Transport Reaction in Mitochondria [6/6]
Endocytotic role of NDK, Phosphins and Dynamin [9/7]
Eph Kinases and ephrins support platelet aggregation [10/6]
EPO Signaling Pathway [18/17]
ER�associated degradation (ERAD) Pathway [14/13]
Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia [23/22]
Erk1/Erk2 Mapk Signaling pathway [28/22]
Erythrocyte Differentiation Pathway [14/7]
Erythropoietin mediated neuroprotection through NF-kB [11/10]
Estrogen-responsive protein Efp controls cell cycle and breast tumors growth [9/8]
Eukaryotic protein translation [9/9]
Extrinsic Prothrombin Activation Pathway [11/7]

FAS signaling pathway ( CD95 ) [30/29]
Fc Epsilon Receptor I Signaling in Mast Cells [30/25]
Fibrinolysis Pathway [10/8]
fMLP induced chemokine gene expression in HMC-1 cells [27/23]
FOSB gene expression and drug abuse [5/4]
Free Radical Induced Apoptosis [9/8]
Function of SLRP in Bone: An Integrated View [2/2]
FXR and LXR Regulation of Cholesterol Metabolism [7/5]

G-Protein Signaling Through Tubby Proteins [7/4]
g-Secretase mediated ErbB4 Signaling Pathway [6/3]
Gamma-aminobutyric Acid Receptor Life Cycle [7/6]
GATA3 participate in activating the Th2 cytokine genes expression [10/7]
Generation of amyloid b-peptide by PS1 [4/4]
Ghrelin: Regulation of Food Intake and Energy Homeostasis [14/9]
Glycolysis Pathway [10/9]
Granzyme A mediated Apoptosis Pathway [11/9]
Growth Hormone Signaling Pathway [23/18]

Hemoglobin's Chaperone [11/8]
HIV Induced T Cell Apoptosis [10/2]
HIV-1 defeats host-mediated resistance by CEM15 [3/2]
HIV-I Nef: negative effector of Fas and TNF [53/49]
Hop Pathway in Cardiac Development [4/3]
How does salmonella hijack a cell [6/5]
How Progesterone Initiates the Oocyte Maturation [19/16]
Human Cytomegalovirus and Map Kinase Pathways [14/13]
Hypoxia and p53 in the Cardiovascular system [23/22]
Hypoxia-Inducible Factor in the Cardiovascular System [15/15]

IFN alpha signaling pathway [9/7]
IFN gamma signaling pathway [6/5]
IGF-1 Signaling Pathway [19/18]
IL 17 Signaling Pathway [16/9]
IL 18 Signaling Pathway [5/2]
IL 2 signaling pathway [21/17]
IL 3 signaling pathway [14/11]
IL 4 signaling pathway [11/9]
IL 5 Signaling Pathway [10/4]
IL 6 signaling pathway [20/20]
IL-10 Anti-inflammatory Signaling Pathway [10/9]
IL-2 Receptor Beta Chain in T cell Activation [35/28]
IL-7 Signal Transduction [15/12]
IL12 and Stat4 Dependent Signaling Pathway in Th1 Development [21/10]
IL22 Soluble Receptor Signaling Pathway [11/8]
Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages [27/20]
Induction of apoptosis through DR3 and DR4/5 Death Receptors [29/26]
Influence of Ras and Rho proteins on G1 to S Transition [25/25]
Inhibition of Cellular Proliferation by Gleevec [20/19]
Inhibition of Huntington's disease neurodegeneration by histone deacetylase inhibitors [4/2]
Inhibition of Matrix Metalloproteinases [9/7]
Insulin Signaling Pathway [20/17]
Integrin Signaling Pathway [36/35]
Internal Ribosome entry pathway [5/5]
Intrinsic Prothrombin Activation Pathway [17/12]
Ion Channel and Phorbal Esters Signaling Pathway [5/5]
Ion Channels and Their Functional Role in Vascular Endothelium [9/6]

Keratinocyte Differentiation [38/32]

Malate-aspartate shuttle [4/4]
Map Kinase Inactivation of SMRT Corepressor [10/9]
MAPKinase Signaling Pathway [80/73]
mCalpain and friends in Cell motility [17/14]
Mechanism of Acetaminophen Activity and Toxicity [5/4]
Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) [47/44]
Mechanism of Protein Import into the Nucleus [11/9]
Melanocyte Development and Pigmentation Pathway [8/6]
Metabolism of Anandamide, an Endogenous Cannabinoid [7/7]
METS affect on Macrophage Differentiation [16/15]
Mitochondrial Carnitine Palmitoyltransferase (CPT) System [4/3]
Monocyte and its Surface Molecules [11/8]
Msp/Ron Receptor Signaling Pathway [6/5]
mTOR Signaling Pathway [21/20]
Multi-Drug Resistance Factors [6/4]
Multi-step Regulation of Transcription by Pitx2 [17/11]
Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation [18/18]

p38 MAPK Signaling Pathway [34/31]
p53 Signaling Pathway [17/17]
PDGF Signaling Pathway [26/24]
Pelp1 Modulation of Estrogen Receptor Activity [7/6]
Pertussis toxin-insensitive CCR5 Signaling in Macrophage [15/10]
Phosphoinositides and their downstream targets. [20/18]
Phospholipase C d1 in phospholipid associated cell signaling [4/2]
Phospholipase C Signaling Pathway [6/5]
Phospholipase C-epsilon pathway [7/5]
Phospholipids as signalling intermediaries [23/18]
Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway [11/9]
PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase [13/10]
Platelet Amyloid Precursor Protein Pathway [10/7]
Polyadenylation of mRNA [4/4]
Presenilin action in Notch and Wnt signaling [14/12]
Prion Pathway [14/12]
Proepithelin Conversion to Epithelin and Wound Repair Control [4/3]
Protein Kinase A at the Centrosome [12/9]
Proteolysis and Signaling Pathway of Notch [6/6]
PTEN dependent cell cycle arrest and apoptosis [18/16]

SARS Coronavirus Protease [8/7]
Segmentation Clock [14/10]
Selective expression of chemokine receptors during T-cell polarization [28/7]
Shuttle for transfer of acetyl groups from mitochondria to the cytosol [8/5]
Signal Dependent Regulation of Myogenesis by Corepressor MITR [4/3]
Signal transduction through IL1R [30/26]
Signaling of Hepatocyte Growth Factor Receptor [34/31]
Signaling Pathway from G-Protein Families [21/19]
Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway [20/19]
Small Leucine-rich Proteoglycan (SLRP) molecules [6/3]
SODD/TNFR1 Signaling Pathway [9/8]
Sonic Hedgehog (Shh) Pathway [10/4]
Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle [7/4]
Spliceosomal Assembly [16/16]
Sprouty regulation of tyrosine kinase signals [15/13]
SREBP control of lipid synthesis [7/7]
Stat3 Signaling Pathway [5/5]
Stathmin and breast cancer resistance to antimicrotubule agents [13/11]
Steps in the Glycosylation of Mammalian N-linked Oligosaccarides [6/4]
Stress Induction of HSP Regulation [15/12]
SUMOylation as a mechanism to modulate CtBP-dependent gene responses [7/6]
Sumoylation by RanBP2 Regulates Transcriptional Repression [10/8]
Synaptic Proteins at the Synaptic Junction [17/13]

T Cell Receptor and CD3 Complex [4/0]
T Cell Receptor Signaling Pathway [34/27]
T Cytotoxic Cell Surface Molecules [12/7]
T Helper Cell Surface Molecules [12/7]
TACI and BCMA stimulation of B cell immune responses. [14/10]
Telomeres, Telomerase, Cellular Aging, and Immortality [19/18]
TGF beta signaling pathway [17/16]
Th1/Th2 Differentiation [19/7]
The 4-1BB-dependent immune response [17/13]
The Co-Stimulatory Signal During T-cell Activation [18/6]
The IGF-1 Receptor and Longevity [11/8]
The information-processing pathway at the IFN-beta enhancer [8/8]
The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails [12/10]
The Role of Eosinophils in the Chemokine Network of Allergy [7/1]
The role of FYVE-finger proteins in vesicle transport [7/4]
Thrombin signaling and protease-activated receptors [17/12]
TNF/Stress Related Signaling [23/21]
TNFR1 Signaling Pathway [29/28]
TNFR2 Signaling Pathway [17/16]
Toll-Like Receptor Pathway [36/28]
TPO Signaling Pathway [19/17]
Transcription factor CREB and its extracellular signals [18/18]
Transcription Regulation by Methyltransferase of CARM1 [8/8]
Transcriptional activation of dbpb from mRNA [4/2]
Trefoil Factors Initiate Mucosal Healing [22/19]
Trka Receptor Signaling Pathway [11/9]
TSP-1 Induced Apoptosis in Microvascular Endothelial Cell [7/7]
Tumor Suppressor Arf Inhibits Ribosomal Biogenesis [12/10]

uCalpain and friends in Cell spread [14/12]

VEGF, Hypoxia, and Angiogenesis [15/13]
Visceral Fat Deposits and the Metabolic Syndrome [8/5]
Visual Signal Transduction [10/3]
Vitamin C in the Brain [6/5]

Y branching of actin filaments [11/9]

beta

beta-arrestins in GPCR Desensitization [11/9]

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